Horizon Pharma USA, Inc. is focused on researching, developing and commercializing innovative medicines that address unmet treatment needs for rare and rheumatic diseases. Horizon has two operating segments, the orphan and rheumatology segment and the primary care segment. Horizon’s strategy is to build a robust and differentiated pipeline and to maximize growth of its marketed rare disease medicines, in particular, KRYSTEXXA, its medicine for uncontrolled gout.