$125 Million

Annexon, Inc.

Underwritten Offering

Bookrunner, December 2023

Annexon, Inc.

Annexon, Inc. (“Annexon”) (NASDAQ: ANNX) is a clinical-stage biopharmaceutical company utilizing a distinct scientific approach to stop C1q and all inflammatory aspects of classical complement pathway activation before it starts. Annexon is developing a fit-for-purpose pipeline of therapeutics designed to provide meaningful benefits across multiple diseases of the body, brain and eye. With proof-of concept data in both Guillain-Barré syndrome and geographic atrophy, Annexon is advancing its mid-to late-stage clinical trials to bring their potential treatments to patients as quickly as possible.